‘Living tools’ at the frontier of vaccine development—A Keystone Symposium workshop by Vish Nene
Africa / AHH / Biotechnology / CBPP / Disease Control / Genetics / Human Health / ILRI / ILVAC / Presentation / Research / Spotlight / Vaccines

‘Living tools’ at the frontier of vaccine development—A Keystone Symposium workshop by Vish Nene

Vish Nene, one of the scientific organizers of the conference and a co-leader of the Animal and Human Health program at the International Livestock Research Institute (ILRI), headquartered in Nairobi, Kenya, gave a particularly lucid talk at the pre-meeting workshop on Novel tools and genomics approaches supporting vaccine development. The following is a transcript of Nene’s talk, lightly edited for clarity and brevity. Continue reading

Reverse vaccinology identifies candidates for an improved vaccine against cattle pneumonia in Africa
Africa / Article / Biotechnology / Cattle / CBPP / Disease Control / ILRI / ILVAC / Kenya / LIVESTOCKFISH / Spotlight / Vaccines

Reverse vaccinology identifies candidates for an improved vaccine against cattle pneumonia in Africa

We used a reverse vaccinology approach to identify 66 Mmm potential vaccine candidates. The selection and grouping of the antigens was based on the presence of specific antibodies in sera from CBPP-positive animals. The antigens were used to immunize male Boran cattle (Bos indicus) followed by a challenge with the Mmm strain Afadé. Continue reading