Vish Nene, one of the scientific organizers of the conference and a co-leader of the Animal and Human Health program at the International Livestock Research Institute (ILRI), headquartered in Nairobi, Kenya, gave a particularly lucid talk at the pre-meeting workshop on Novel tools and genomics approaches supporting vaccine development. The following is a transcript of Nene’s talk, lightly edited for clarity and brevity.
What happened in the Feed the Future Mali Livestock Technology Scaling Program (FTF-MLTSP) in early 2018? Open Day and stakeholder consultation for the program, PPR vaccine deployment, and market monitoring.
The most recent progress report from the Feed the Future Mali Livestock Technology Scaling Program describes some successes and swift progress made in recent months towards achieving these goals as well as some new challenges the program is facing.
We used a reverse vaccinology approach to identify 66 Mmm potential vaccine candidates. The selection and grouping of the antigens was based on the presence of specific antibodies in sera from CBPP-positive animals. The antigens were used to immunize male Boran cattle (Bos indicus) followed by a challenge with the Mmm strain Afadé.
For almost thirty years, the International Laboratory for Research on Animal Diseases (ILRAD) then ILRI benefited from a strong research program in the epidemiological sciences. Over time, it progressively broadened its coverage in disease, disciplinary and geographic terms. The results of this work have now been assembled in this impact narrative, which carefully documents the wide range of issues addressed by the teams of researchers, and presents them in an illustrated and highly readable format.
There has been a long-term, consistent and highly productive engagement between research institutions and funding bodies of the United Kingdom and the International Livestock Research Institute (ILRI) and its predecessors, the International Laboratory for Research on Animal Diseases (ILRAD) and the International Livestock Centre for Africa (ILCA).